LSD Harm Reduction Guide

Effects

• ✦Visual and auditory distortions
• ✦Intensified emotions and introspection
• ✦Time distortion
• ✦Ego dissolution at high doses
• ✦Synesthesia (senses blending)
• ✦Increased empathy and connectedness

Duration

8–12 hours (peak 3–5 hours, afterglow up to 24 hours)

Dosage

Individual sensitivity varies. Always start at the lower end if you're new to this substance.

Risks

• ⚠Anxiety and panic reactions, especially at high doses
• ⚠Difficult experiences ('bad trips') if mindset or environment isn't right
• ⚠HPPD (persistent visual disturbances) in rare cases
• ⚠Exacerbation of underlying mental health conditions
• ⚠Dangerous behaviour if taken in an unsafe environment

Harm Reduction Tips

• ✓Start with a low dose (50–75 µg) if it's your first time
• ✓Choose your environment carefully — familiar, safe, comfortable
• ✓Have a trusted sober trip sitter present for higher doses
• ✓Test your substance with a reagent kit (Ehrlich + Hofmann) before use
• ✓Avoid if you have a personal or family history of psychosis or schizophrenia
• ✓Clear your schedule — plan for the full day plus recovery time
• ✓Prepare a 'trip kit': water, snacks, a blanket, music you love
• ✓If a difficult experience starts, change the setting, lie down, and breathe

Dangerous Combinations

Always research interactions before combining any substances.

• ✕Lithium — risk of seizures and cardiac events; never combine
• ✕Tramadol — seizure risk
• ✕Cannabis — can dramatically amplify anxiety and paranoia at high doses
• ✕Stimulants — cardiovascular strain